Background: The incidence of COVID-19 is at risk in patients with comorbid hypertension and diabetes mellitus, male sex, and active smokers. Cancer is associated with immunosuppressive reactions, cytokine overload, suppression of proinflammatory agent induction, and impaired dendritic cell maturation.Based on another study at a hospital in Wuhan, it was found that cancer patients from the epicenter of the viral epidemic had a higher risk of being infected with SARS-CoV-2. Based on the Based on the description above, the researchers wanted to know the co-incidence of COVID-19 in cancer patients at H. Adam Malik Hospital and USU Hospital Medan. Methods: This study is a descriptive study to assess the co-incidence of COVID-19 in cancer patients at H. Adam Malik Hospital and USU Hospital Medan. The sample of this study were all cancer patients at H. Adam Malik Hospital and USU Hospital Medan who met the inclusion criteria. Data classified into categories or code to make it easier to tabulate data.All data is processed and displayed in a frequency distribution table with the help of statistical software. Results: It was found that from 891 patients, the average age of COVID-19 patients with cancer was 44 years while 12 patients (1.34%) experienced COVID-19 and Cancer Coincidence. The most cases were breast cancer patients with 3 cases. Conclusion: It was found that 12 patients (1.34%) had COVID-19 and cancer with the most cases were breast cancer, 3 cases and most of them have COVID-19moderate degree.