Comparison of diferent doses of ketamine for minor obstetric and gynaecologic procedures

Ketamine in two different doses (1 mg/kg and 2 mg/kg IV) after diazepam 0.2 mg/kg IV was administrated to 100 females for minor obstetric and gynecologic procedures after premedication with either atropine 0.01 mg/kg i.m. or with atropine 0.01 mg/kg and promethazine 0.5 mg/kg i.m., anaesthesia was satisfactory and mild but clinically insignificant respiratory depression was observed in all the four groups. Addition of promethazine to the premedication significantly reduced the postoperative nausea & vomiting as well the emergence delirium (P < 0.05).