The problem of water pollution by heavy metals is all over the world especially in developing countries. This problem of groundwater contamination with heavy metals becomes one of the most important environmental issues because some of these metals are toxic in their nature even at low concentrations. Groundwater is the major source of drinking water in urban and rural areas in Yemen, and is an important water supply source worldwide. Groundwater in Lahj Governorate is used exclusively to satisfy the needs of different sectors which use water for drinking, domestic irrigation and industrial use. The heavy metals can cause occupational and accidental harm to humans, and can contaminate water, soil and air as well. The aim of this study is to analyse some heavy metals from groundwater in Lahj Governorate of Yemen and its relation to the developed industrial activities. Twenty groundwater samples were collected from different wells in Lahj Governorate. The groundwater samples were analysed using (AAS) Atomic Absorption Spectrophotometer. The mean concentration of Cadmium (Cd), Copper (Cu), Zinc (Zn), and lead (Pb) is measured. The concentration of these heavy metals ranged from 0 to 0.0735 ppm, 0 to 0.0756 ppm, 0.017 to 0.73 ppm, and0 to 0.4434 ppm respectively.