Recent epidemiological studies have revealed that incidence of trichomoniasis is more than 170 million cases annually at global level. In India, it has increased from 2 to 7 % of all sexually transmitted infections. Cases of trichomoniasis is increasing with time due to development of industries, lifestyle modulation, inadvertent encroachment of mass media and advances in various types of marketing strategies. Hence, the present study was aimed to determine the incidence of vaginal trichomoniasis in reproductive age group belonging to rural teaching hospital with tertiary healthcare facilities in vidarbha region and also to critically appraise the therapeutic modules. This hospital based analytical study was carried out between 1st January 2014 to 31st December 2016 in Obstetrics and Gynaecology Department of A.V.B. Rural Hospital on 304 women of reproductive age group belonging to rural vidarbha region. The data were collected from in-depth interview of unit heads,professors, associate professors, assistant professors, Junior residents as well as patients. In A.V.B. Rural Hospital, Wardha, the incidence of Vaginal Trichomoniasis was 21.95% in 2014, 34.15% in 2015 and 37.80% in 2016.Drugs prescribed to patients were Doxycycline (63.41%), Metronidazole (81.09%), Ofloxacin+Ornidazole (18.90%), Ranitidine (100%) and Clid-V Pessary (80.18%). Statistical significance was calculated by using z-test for single proportion.Software used in analysis was SPSS 22.0 version and GraphPad Prism 6.0 version and the findings were found out to be statistically significant. Male partners of the drug recipients were also examined and treated simultaneously and advised for follow up investigations and treatment for outcome appraisal. Incidence of vaginal trichomoniasis is increasing at an alarming rate in rural vidarbha region and there is no significant change in final outcome of recently prescribed treatment modules. Intervention strategies like public awareness campaign highlighting consequences of vaginal trichomoniasis in males and females and counselling of both partners are recommended at this juncture for better and bright future.