Sodium hypochlorite is a globally used irrigant in dental practice during root canal treatment. Although, generally regarded as being very safe, some potentially severe complications can arise when it comes in contact with soft tissues, skin or even clothing. Unintentional extrusion of sodium hypochlorite beyond the root apex results in widespread soft tissue or nerve damage. Its chief shortcomings in dentistry are the noxiousness of its action to vital tissues. In this article, we review the possible difficulties that can arise with sodium hypochlorite use during endodontic treatment, discuss the appropriate management and actions that can be taken to lessen danger, and provide specifics of suitable management in the rare cases of alleged tissue injury and damage.
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