Studies have revealed that burnout inactivates workers reducing their performance at work place. School factors such as lack of physical facilities, human resource and insecurity increase level of burnout which has is linked to underperformance by head teachers and translate to poor performance in schools. In Butula Sub-county, preliminary survey involving five head teachers indicated that head teachers were experiencing high levels of burnout. The objective of the study was to determine school factors that influence burnout among head teachers in public primary schools in Butula Sub-County, Kenya. A conceptual showing the relationship between independent variable (school factors) and dependent variable (burnout among head teachers) was used to guide the study. The findings of the study were that school factors invariably influenced burnout among head teachers. The study concluded that indeed school factors do influence burnout among head teachers. The study recommended that head teachers should adopt methods of dealing with burnout by addressing school factors that influence burnout. The findings of this study are significant to stakeholders in education as they provide information that can be used in policy formulation that can minimize burnout among head teachers in schools.