In Islamic world, there are six most reliable hadith collections. In particularly, they are Sahih al-Bukhari, Sahih Muslim, Sunan Abi Dawud, Sunan al-Nasa’I, Sunan al-Tirmidhi and Sunan ibn Maja. Other than Sahih al-Bukhari very little has been written about the other five collections. The reason of that only just recently that a full translation of the Sunan al-Tirmidhi has become available in English [1]. However, Isa Tirmidhi’s ideas were famous for its reliability in European scholars until its publication. About Hadith and its importance, there are also different thoughts among researchers. Some says they are main sources after Qur’an and others say they are fabricated stories. When the talk goes on about Hadith and its importance, most scholars prefer to clarify their ideas with Sunan al-Tirmidhi. When and how was Abu Isa Tirmidhi known in Europe? And what kind of reasons persuaded to study Sunan al-Tirmidhi? This research intends to analyze works about Abu Isa Tirmidhi that published in European countries. It will be an attempt to analyze and compare scientific works how they explained Abu Isa Tirmidhi and his Hadiths. More than ten works of European scholars that discussed to show the research levels of Abu Isa Tirmidhi. The qualitative study used the literature review framework and obtained research data through document analysis. In general, Abu Isa Timidhi’s scientific legacy can be proven as the most vital sources to learn and explain Hadith in Europe.