Objective: To study the levels of lipid profile during second and third trimester pregnancy. Introduction: Currently, maternal prepregnancy body mass index (BMI) has increased and reflecting the overall increase in the prevalence of obesity (1). Higher BMI during pregnancy have negative implications on pregnancy outcomes, results affect the burden on health of both mother and the infant at risk. Material and methods: This case control study was conducted at the department of gynecology & obstetrics, Lalla Ded Hospital a tertiary care hospital, by enrolling antenatal cases for the the study. The study was conducted on 25 obese women (BMI>30Kg/ m2). Results: In obese second and third trimester, the mean cholesterol levels were 215.35±15.8 229.82±16.2 mg/dl respectively. The mean HDL levels were 43.5±5.8 and 40.6±5.2 mg/dl. The mean TGL levels were 179.23±36.5 and 190.58±39.4 mg/dl. Whereas, non-obese second and third trimester had decreased total cholesterol levels. Conclusion: Overweight/obese women have more atherogenic lipid profile than normal weight women during second and third trimester pregnancy, which may help to predict the pregnancy outcomes.
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