Fibromyxoma represents a rare benign neoplasm that mostly affects the posterior region of the mandible. It represents 0.5 to 17.7 % of odontogenic tumors: the third most frequently occurring type. This case report represents a patient with fibromyxoma of left mandible. A 42 year old female was referred for the evaluation and management of non-tender swelling on left face region that had gradually increased in size over 4 months duration. The examination revealed a palpable firm mass. Mild blanch mucosa with no ulceration was observed over swelling. Preoperative radiographs and computed tomography shows well defined multilocular expansile lesion. Surgical segmental resection of mandible under general anesthesia was performed via the extra oral approach followed by reconstruction with Titanium Recon plate of 2.5 mm. A histopathological examination confirmed the diagnosis of fibromyxoma. In conclusion, the radiological examination by means of CT and MRI plays an important role in the diagnosis of a fibromyxoma and in the differential diagnosis from other pathological entities such as the ameloblastoma. Patients must be monitored for at least two years postoperatively in order to diagnose possible recurrence.