Objective: Review omega 3 and omega 6 in childhood diet. Data Sources: From previous Literatures, reviews and studies as well as medical websites (PubMed, MD consult, Medscape) and Scientific Journals data- bases were searched from the start date of each data- base. Study Selection: Selection was done by supervisors for studying new advancement in omega 3 and omega 6 in childhood dietinpediatric and studies that addressed the important of omega 3 and omega 6 in childhood diet. Data Extraction: Data from published studies were manually extracted and summarized. Study quality assessment included whether ethical approval was gained, prospective design, eligibility criteria specified, appropriate controls used, adequate follow-up achieved and defined outcome measures. Data synthesis: In this review the data found that several studies of omega 3 and omega 6 in childhood diet to know which omega 3 and omega 6 can used in several diseases Findings: A total of 50 studies were included in the review as they were deemed eligible by fulfilling the inclusion criteria. Of these 50 articles, included in this review, 32 were Omega 3 and omega 6 in child diet and 18 were omega and diseases Studies indicate that omega 3 and omega 6can used in the treatment of some diseases. Conclusion: Omega-3 and Omega-6 are essential fatty acids and are important for human health and diet must be balanced in the omega-6 and omega-3fatty acids decreasing omega-6 and increasing omega-3fatty acids.