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Antimicrobial action of 2-pyrrolidinone identified from nephila antipodiana

Author:

Mahreen Mahajan

Subject Area:

Life Sciences

Abstract:

Spider’s web from Nephila antipodiana has been identified for producing a significant repellant activity against pests and ants. In order to investigate the repellant activity, screening of various compounds in the web was performed by GC-MS. An alkaloid namely, 2-pyrrolidinone was observed to act as a predator deterrent in species of moths, caterpillars and ants. For analyzing the feasibility of this alkaloid as an anti microbial action, antimicrobial studies were performed. The evaluation was done by well diffusion assay on two species of bacteria and fungi plant pathogens. Different concentration of 2-pyrrolidinone were loaded into the wells and the zone of inhibition was measured. Inhibition curves were compared, to check the effect of 2-pyrrolidinone between the bacterial and fungal species.

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