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Bidirectional interface between periodontitis and metabolic syndrome –

Author:

Dr. Shaik Sharmila Sufia, Dr. Shabnam Sufia Shaik and Dr. Madhavi Kondeti

Subject Area:

Life Sciences

Abstract:

Periodontitis is the most common multifactorial oral disease of microbial origin characterized by loss of attachment apparatus of tooth leading to edentulism if left untreated. It releases systemic and local inflammatory byproducts which are the possible risk factors for major components of the metabolic syndrome such as Diabetes, obesity, hypertension. Metabolic syndrome is a complex pathology that constitutes of increased plasma glucose, hypertension, hypertriglyceridemia, low HDL cholesterol, elevated abdominal circumference. The presence of above any 3 factors constitute this syndrome. Therefore, this reviewarticle will emphasize on iniquitous relationship between periodontitis &metabolic syndrome, their pathophysiology and evidence / lack of evidence in supporting their association in disease progression.

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