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Formulation, Characterization and Evaluation of Curcumin-Cholesterol Phytosomal Complex

Author: 
Aloisio Mateus Fiuza Sanha, Satyender Kumar and Pramod Kumar Sharma
Subject Area: 
Health Sciences
Abstract: 

Turmeric as been long known for its medicines properties and it is the major source for curcumin and it helps in management of various health conditions such as antioxidant, inflammatory, hyperlipidemia, anxiety and metabolic syndrome. Despite these advantages when administered alone curcumin does not attain its full therapeutic effect because of its poor absorption, fast metabolism and rapid elimination. To overcome this barrier for its efficient delivery, curcumin was incorporated into phytosome technology by reacting it with cholesterol. The term phytosome can be divided into two parts, “phyto” means plant while “some” means cell-like. Phytosome is a evolving technology in which the phytochemical agent is bounded with lipid agent. Thus, it results in increased absorption, stability which leads to better bioavailability and therapeutic effect in the treatment of various health conditions as compared to delivery of the herbal compound alone.

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