Sexual health is an essential part of good overall health and well-being. Sexuality is a part of human life and human development. A good sexual health is significant across the life span and it is critical in adolescent health. When children grow up both physiological and psychological changes occurs in different stages of development of life. Imphal city of East and West district is selected as a study region. For intervention 5 schools from east region and 3 schools from west regions were selected randomly. The total sample for the study was 200 adolescent girls using simple random sampling. The questionnaire comprising of Socio-economic information and Attitude assessments consists of 62 statements with five point likert scale with response and score as strongly agree assigned ‘5’, agree ‘4’, undecided ‘3’, disagree ‘2’, and strongly disagree ‘1’. After obtaining pre test information intervention program administered to adolescent girls with audio-visual aids and teaching strategies for 3 months duration. Further, post test assessment was elicited. Majority of the study sample were in the age group of 15 years, studying in 8th Standard with one sibling, first ordinal position and 60-69% in academic performance. Majority were nuclear family, from urban area and income between Rs.20,001-30,000. Majority (49.0%) got menarche in the age group of 13-14 year, had regular menstrual cycle and had five days menstrual flow with problems as stomach ache and back ache. Finding indicates pretest mean attitude score found to be 48.8% as compared to post test 73.0%. The enhancement of attitude score from pre-test to post-test found to be 24.2%. The data subjected for statistical test reveals that the enhancement of knowledge found to be statistically significant (t =55.20*, p<0.05).