CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Paratransgenesis involving microbes: deserving approach for the control of vector borne diseases

Author: 
Vitthalrao B. Khyade, Mansi Avinash Adagale, Apurva Baban Tamhane and Shubhangi Shankar Pawar
Subject Area: 
Life Sciences
Abstract: 

There is cause of severe morbidity and mortality throughout the world by diseases that are transmitted by arthropods. The burden of many of these diseases is borne largely by developing countries. Advances in vector genomics offer new promise for the control of arthropod vectors of disease. Radical changes in vector-biology research are required if scientists are to exploit genomic data and implement changes in public health. Use of chemicals to control vector borne diseases often exert influence associated with environmental toxicity and affects adversely on human health. Moreover, this method leads to potentiate the vector for resistance. The strategy for the control of vector borne diseases should be paratransgenic. Symbiotic or commensal microbial pathogens should transformed to express products of gene that interfere with the transmission of pathogen. That is to say the genetically modified microbes are to be re-introduced back to the insect (vector). This method definitely, decrease the ability of the vector to transmit the pathogen into the human body. The paratransgenic method if utilized efficiently, it may reduce rate of for example Trypanosoma cruzi, the causative agent of Chagas disease, the triatomine bug, Rhodnius prolixus, and Leishmania donovani by the sand fly Phlebotomus argentipes. There are many effector biomolecules (example: antimicrobial peptides and specific single chain antibodies), currently being explored for the activities of “anti-parasite” in the systems to control vector borne diseases. This method deserve environmental protection and exert positive influence on the health of human being. However, the field application of laboratory-based evidence of paratransgenesis imposes the use of more realistic confined semi-field environments. Paratransgenesis could prove very useful in mosquito species that are inherently difficult to transform or in sibling species complexes. It is a much more flexible and adaptable approach than the use of genetically modified vector (ex. Mosquitoes) because effector molecules and symbiotic bacteria can be replaced if they do not achieve the desired result. Paratransgenesis may therefore become an important integrated pest management tool for the Control of Vector Borne Diseases.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran