CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Rp- hplc facilitated quantitative analysis of tectorigenin in the different species of iris plant and evaluation of its invitro anticancer potential

Author: 
Sajad H. Wani, Asif amin, Shahnawaz N. Sofi, Taseem A. Mokhdomi, 1Shoiab Bukhari, Qazi Parvaiz Hassan and Raies A. Qadri
Subject Area: 
Life Sciences
Abstract: 

A simple HPLC-UV-DAD method was developed for rapid identification and quantitation of tectorigenin in five species of genus Iris viz Iris crocea, Iris ensata, Iris germanica, Iris kashmeriana and Iris spuria growing wild in Kashmir valley. The analysis was performed by using Chromolith RP-18e analytical column (5 μm; 4.6 mm × 100 mm) at isocratic elution of methanol and water (30:70, v/v) with diode array detection at 265nm. The calibration curve showed good linearity (r2 > 0.998) within test ranges and recoveries were 98.2 to 101.2%. The optimized method was successfully applied for the analysis of tectorigenin in 12 samples of five species of Iris collected from different eco-geographical zones. The tectorigenin content in investigated samples was greatly variant ranging from 1.08% to 8.84% with a maximum in Iris germanica collected from Gulmarg region of Kashmir valley. The method established in this paper is simple and reliable and could easily be used for the qualitative analysis of tectorigenin in Iris species. Furthermore, to evaluate anti-cancer properties, different concentrations of tectorigenin were tested against colon cancer cell line, Caco-2 using MTT cell proliferation assay. The results showed a prominent growth inhibition in a concentration dependent manner with maximum inhibition at a concentration of 100µM.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran