Effect of topical tetracaine gel %4 on intensity of pain due to intramuscular injection of dpt vaccine for 18 month of age

Introduction: Intramuscular injection is an invasive and painful method for medication. Previous studies have indicated that tetracaine has ability to decrease pain via decreasing transmission and perception. The effect of local tetracaine severity of pain during DPT vaccine IM injection is not known. The aim of this study was to evaluate if topical Tetracaine reduce the pain of IM DPT injection compared to placebo. Materials and methods: In this RCT, 40 children were taken and divided into case and placebo group using a randomized Allocation sampling . In case group used from topical tetracaine gel %4, 30 second before DPT injection; in placebo group used from lubricant gel (placebo) before DPT injection. Data was collected using FLACC scale and were analyzed with wilcaxon signed rank test. Results: Results showed that tetracaine could not significantly decreased the severity of pain due to DPT vaccine IM injection in case group as compared with placebo group (p>0/05). Conclusion: Finding of this study indicated that topical tetracaine Application could not play an important role in decreasing of pain during DPT vaccine IM injection .Although it did lead to faster recovery time. However, more studies are needed to determine of effect of pain reduction strategies.