CALL FOR PAPERS

CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

 

 

 

Prevalence of serum vitamin b12 deficiency and correlation between serum vitamin b12 deficiency with dosage potency and duration of ppi use among elderly using long term PPI

Author: 
Dr. Mudasir Ahmad Sofi MD, Dr. Masood Tanvir, Dr. Rakib Ahmad Wani and Dr. Sobia Nisar
Subject Area: 
Health Sciences
Abstract: 

Introduction: Vitamin B-12, also called Cobalamin Water soluble vitamin. It is the largest and structurally complex vitamin. Sources of Vitamin B12 are Produced by microorganisms (bacteria/fungi) inhabit in gut, Plants do not produce or contain VitaminB12. Liver, Kidney, Muscle, Egg, Milk, Cheese and other dairy products, Seafood and Foods fortified with B12 are also sources of the vitamin B12. Individuals who lack intrinsic factor have a decreased ability to absorb B12.Gastric acid releases the vitamin from food particles. Therefore antacid and acid-blocking medications may inhibit absorption ofB12.In addition some elderly people produce less stomach acid thereby increasing their probability of B12deficiencies. Methodology: In this observational study, 102 study patients were included on the basis of inclusion and exclusion criteria. The data was collected by administering a clinical questionnaire, relevant medical, drug history and dietary history. All baseline investigations, serum vitamin B12 level was investigated to document the deficiency. Data was analyzed through Epinfo using student`s t-test, Chi square test. p<0.05 was considered statistically significant. Result: It was observed that only (6.9%) of patients are deficient and (11.8%) are on borderline while as (81.4%) of study patients are not having any abnormality with regard to vitamin B12 deficiency. Among 102 patients ; 80 patients were prescribed PPI for peptic ulcer disease and rest 22 patients were having co morbid disease where PPIs were prescribed prophylactically. Around (6%) of patients are having deficiency in vitamin B12 who receive 40 mg dosage of PPI while as around (94%) of patients are not having any deficiency. However, around 12 percent of patients are having vitamin B12 deficiency who received 80 mg dosage of PPI and (88.2%) does not report any deficiency on this dosage. Discussion: The present study deficiency in Vitamin B12 alternatively named as cobalamin is a disorder that is most commonly seen in individuals who are beyond 59 years of age with a supporting prevalence of (10-40%). Vitamin B12 deficiency is generally thought to be synonymous with pernicious anemia (intrinsic factor deficiency); however, studies suggest that pernicious anemia is rare among types of vitamin B12 deficiency in the older population. Research conducted by Scarlet, suggested that most older adults with vitamin B12 deficiency have a normal Schillings test, but do not adequately absorb food-bound cobalamin.

PDF file: 

Announcement

  • FAST PUBLICATION : October 2022
  • IMPACT FACTOR: 7.992
  • QUALIS INDEXING
  • HIGH IMPACT FACTOR
  • INTERNATIONAL JOURNAL OF CURRENT RESEARCH

IJMCE RECOMMENDATION

ONLINE PAYPAL PAYMENT

CURRENT ISSUE

NEWS

CHIEF EDITOR
Rosane Cavalcante Fragoso, Brasil
ASSOCIATE CHIEF EDITOR

   

Jean-Marc SABATIER
Chief Scientific Officer and Head of a Research Group
France

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

EDITORIAL BOARD

Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran