B cell chronic lymphocytic leukaemia (B CLL) is the most common form of leukemia and occurs with a male predomi¬nance. Chronic lymphocytic leukemia (CLL) infiltrating the skin is uncommon and can present in many different ways. The reported specific skin lesions include nodules, papules, infiltrates, plaques, ulcerations and exfoliative eryth¬roderma. Here we report a case of atopic dermatitis as an usual presentating feature of CLL.