CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Carbapenemase producing pseudomonas aeruginosa: A cause of concern

Author: 
Dr. Sanchari Das and Dr. Silpi Basak
Subject Area: 
Health Sciences
Abstract: 

Background: Pseudomonas aeruginosa is one of the most important cause of Healthcare associated infections. Carbapenems are often used as a last resort for treating serious infections caused by multidrug resistant Pseudomonas aeruginosa. Carbapenamases are β-lactamases which cause carbapenem hydrolysis. Aim: The present study was undertaken to detect the incidence of Carbapenemase producing Pseudomonas aeruginosa from clinical isolates. Material and Methods: 150 clinical isolates of Pseudomonas aeruginosa were studied for antibiotic susceptibility profile by Kirby Bauer disk diffusion method as per CLSI guidelines, 2016. All Pseudomonas aeruginosa strains were screened for Carbapenemase activity by Classical Hodge test. Metallobetalactamases (MBL) production was detected and confirmed by Disc potentiation (DP) test using Imipenem and Imipenem plus EDTA and by E-test. Klebsiella pneumoniae Carbapenemases (KPC) production was detected by combine disc method using Imipenem and imipenem plus Phenyl boronic acid (PBA). Both MBL and KPC producing strains were detected by Imipenem disc and disc containing Imipenem plus PBA plus EDTA. Class D carbapenemase i.e, OXA β– lactamases were not included in our study. Results: The highest sensitivity was observed to Colistin 149(99.3 %), followed by Imipenem 107(71.3%). 43(28.7%) Pseudomonas aeruginosa strains were Classical Hodge test positive, 6(4%) were positive for MBL only by DP test. 15(10 %) were positive for KPC only and 34 (22.6 %) were positive for both MBL and KPC. These 40 MBL producing strains were positive by MBL E test. Conclusion: All Pseudomonas aeruginosa strains must be screened for carbapenamase production in Cinical Microbiology laboratory.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran