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A comparative clinical study of Chirbilwa (Holoptelea integrifolia planch) bark Ghanwati and Navak guggulu in overweight
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Life Sciences
Abstract:
A single blind clinical trial conducted for a period of 3 months to evaluate the effect of the bark of Holoptelea integrifolia (Family- Ulmaceae) on body weight and associated metabolic disorder in over weight human volunteers (BMI >25/m2). The trial and positive control groups received GHANAVATI (Holoptelea integrifolia) and NAVAKA GUGGULU (Standard Ayurvedic Preparation) respectively 30-60 minute before lunch and dinner. At baseline, after 3 months, significant improvement in body weight, BMI, chest, abdomen, waist, arm and thigh, biceps and triceps circumference, as well as haematological parameter (Hb, serum cholesterol, triglyceride, HDL, LDL, VLDL) were observed in the GHANAVATI group compared with NAVAKA GUGGULU. Bark extract of Holoptelea integrifolia may prove to be a useful tool in dealing with the emerging global epidemics of obesity, hyperlipedemia and cardio- metabolic disorders.
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