
In low resource - countries like Benin, HIV viral load is rarely available for monitoring antiretroviral treatment, which is generally based in these settings on clinical assessment together with T-cell CD4 count. In this study, we present our experience of setting up HIV viral load in Cotonou and the relative contribution of this test in monitoring such patients. From May 2013 to January 2014, 139 participants aged above 15 years were tested for both T-cell CD4 count and HIV viral load. We observed that HIV viral load was above 3 Log10 copies/ml in 15 participants (10.8%) though their CD4 count was above 350 cells/µl. HIV viral load could help for early detection of patients with incomplete virologic response to antiretroviral treatment in Cotonou.