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Quantification of novel dpp4 inhibitor-saxagliptin by spectrophotometric and chromatographic techniques: brief review

Author: 
Chandrika Sailaja, K., Yoganarasimha Rao, B., Pujitha, S., Akhil Kumar, P., Yashwanth, G., Ratna Kumari, Y., Srikanth, I. and Suresh Kumar, J.N.
Subject Area: 
Health Sciences
Abstract: 

A review is presented on different analytical techniques used for quantitative analysis of novel Dipeptidyl peptidase-4 inhibitor (DPP-4) - Saxagliptin. Efforts have been made to collate all the relevant references to the extent possible. The review discusses the advantages and disadvantages of the cited analytical techniques, which will help to give insights into the methods used for estimation of saxagliptin, from clinical isolates and from its dosage forms. The review highlights the basic as well as advanced techniques performed for estimating saxagliptin. The techniques illustrated here have been demonstrated to be useful for quantitative determination of saxagliptin and may find application in analyzing other related properties.

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