
Acanthaceae is a family of dicotyledonous flowering plants containing almost 250 genera and about 4,000 species. Acanthaceae is a family well known for its medicinal values due to the presence of valuable phytochemical compounds. The knowledge of the properties of the medicinal plants is growing as a result of which research and testing are been carried out throughout the world s they could be a alternative option for allopathic medicine. In the present study the analysis of Phytochemical compounds and antimicrobial activity of seven plants samples belonging to Adathoda beddomie, Neelagirianthasis Sp, Justeceae gendurusa, Neelagirianthasis hemitomie, Berleria priorities, Adathoda zylanica and Hemigraphis corolata was analyzed where in it was found that tannins was present in all the plant species which indicate that tannin plays a major role in the medicinal property of the plant species. The solvent extract showed antimicrobial activity against all the clinically isolated microorganisms. The maximum antagonistic effect was seen against pseudomonas species.