Background: Postnatal depression is a serious mental health problem among women and its consequences have important implications for the welfare of the family and the development of the child. Objectives: The purpose of the study are: 1. To assess depression among the postnatal mothers residing at the regional hospital Kullu and with the families. 2. To find out the association between depression in postnatal mothers residing at the regional hospital Kullu with selected demographic variables. Hypothesis: H0-There will be no significant association between Postnatal depression with their selected socio demographic variables. H1- There will be significant association between the Postnatal depression with their selected socio demographic variables. Methods: Cross sectional descriptive survey design was used. 60 sample were selected at regional hospital Kullu by using simple convenient sampling technique .Edinburgh Depression Scale –Long form used to assess the level of postnatal depression among postnatal mothers. Level of postnatal depression was assessed by using descriptive and inferential statistics. Result: In this study findings reveal that majority of postnatal mothers in regional hospital Kullu belongs to Hindu religion 96.6% , 1.6% muslim and 1.6% christian Majority of postnatal mothers were lliterate in regional hospital Kullu was 96.6% and 3.3% were illiterate. Majority of postnatal mothers belongs to joint family 61%, nuclear family 26.6% and 3rd generation 11.6%. Conclusion: The study finding revealed that postnatal mothers residing at regional hospital Kullu are more affected with depression as compare to postnatal mothers residing with their families. The finding of the study served as a basis for the nursing professionals and students to conduct further studies regarding depression on health status of postnatal mother.