“Covid-19 infection a trigger to cold agglutinin hemolytic anemia”

Cold agglutinin antibodies are autoantibodies causing hemolysis at a lower temperature which can be triggered by various infections like covid-19, mycoplasma pneumonia and numerous other virus causing flu like symptoms. Cold agglutinin antibodies cause multisystem immune mediated dysfunction;haematological and circulatory are the major ones affected. Presently, no definite treatment is available for immune mediated cold agglutinin disease secondary to covid 19 infection.