Aim: To review the literature on the advances on enamel regeneration and the challenges faced. Objective: To compile the various advances in the field of enamel regeneration. Background: Enamel is the outermost covering of the crown of the teeth. It consists of 96% organic material and 4% inorganic material. The most abundant protein in enamel is amelogenin. Since it's the outermost covering it is prone to damage and dental caries despite of its strong structure. Reason for the project: The ameloblasts degenerate after enamel formation and so enamel cannot be regenerated in case of damage. There are many ceramic materials and metals which are used to replace enamel but none of it matches enamel in functions -both protective and aesthetic. Studies in this field would bring about a drastic change in the field of dentistry.
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