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Antibiogram of bacterial isolates From, Tracheal aspirate of ICU patients at tertiary care hospital in western, Rajasthan, India

Author: 
Soni Priyanka, Parihar, R. S., Khatri, P. K., Soni laxman Kumar, Agarwal Ramesh, Duggal Swati and Verma Shashikala
Subject Area: 
Life Sciences
Abstract: 

Introduction: Respiratory infections in critically ill patients are associated with high morbidity and mortality. Patients who are mechanically ventilated are at high risk of acquiring respiratory infections due to complex interplay between the endotracheal tube, host immunity and virulence of invading bacteria. To initiate empiric antimicrobial therapy knowledge of local antimicrobial resistance patterns are essential. Materials and Methods: This study was based on 245 patients of ICU of M.D.M. hospital, Dr. S.N. Medical College, Jodhpur, Rajasthan, India. Patients with positive endotracheal aspirates were included in this study. Data regarding microbial isolates and their culture and sensitivities were recorded. Results: The organism obtained were Klebsiella sp, Staph. aureus, Pseudomonas sp, Acinetobacter sp, Citrobactor, E.coli, Proteus Whereas Klebsiella sp, were the most frequently isolated bacteria. All the organisms more or less showed both sensitive and resistance pattern but Acinetobacter sp was show resistant to all the antibiotics except imipenam and levofloxacin. Conclusions: Gram negative organisms mostly susceptible to fluoroquinolones&Carbapenem group of antibiotics which were the predominant isolates in our critical care setup. A local antibiogram for each hospital, based on bacteriological patterns and susceptibilities is essential to initiate empiric therapy, to prevent poor outcomes and help in framing the appropriate institutional antibiotic policy.

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