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Anticancer potential of green synthesized silver nanoparticles: a review

Author: 
Patil Sunita, Rajeshwari Sivaraj, Venckatesh, R. Vanathi, P. and Rajiv, P.
Subject Area: 
Life Sciences
Abstract: 

Silver nanoparticles synthesis is a vastly growing area of research adding day by day new applications in various fields. There are a number of physical and chemical methods which are energy and capital intensive and employ toxic chemicals. Thus more and more researchers are involved in green synthesis of nanoparticles from plants, fungi and bacteria. Use of silver nanoparticles in the field of biomedical nanotechnology and nanomedicine is rapidly increasing because of their antimicrobial, anticancer, antioxidant property and less toxicity. Cancer is one of the most deadly diseases treated by conventional chemotherapeutic agents exhibiting poor specificity and dose limiting toxicity. The present study is aimed to throw a focus on the potential of green synthesized silver nanoparticles cytotoxicity on skin cancer cell lines and its application as an anticancer agent. Green silver nanoparticles from different origin have the ability to defend against various types of cancers. The data available for comparison are mostly in vitro studies and therefore in the coming days in vivo studies, development of formulation and clinical trials are required for utilizing the anticancer potential of silver nanoparticles in practice.

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