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Bioassay- guided fractionation and anti-fungal activity studies on pisonia grandis r.br.

Author:

Shubashini K. Sripathi and Poongothai, G.

Subject Area:

Life Sciences

Abstract:

Pisonia grandis is an herb claimed to be used for treatment of various diseases by local folks. Since, this plant possesses many medicinal properties; there are not many scientific studies carried out on this plant which promoted us to pursue a systematic pharmacological evaluation of Pisonia grandis leaves to verify their medicinal properties. Bioassay- guided fractionation of ethanol extract of leaves of Pisonia grandis was studied for its anti-fungal activity against microorganisms Candida albicans, Aspergillus niger, Pencillium citrinum and Monascus purpureus by disc diffusion method. The ethanol extract showed good anti-fungal activity against Monascus purpureus comparable to standard clotrimazole.

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