Clear Cell Carcinoma of the Endometrium: A case report and Review

Endometrial cancer is the most common gynecologic malignancy, and according to the Surveillance, Epidemiology and End Results (SEER) statistics for 2006 to 2010 it is the fourth most common cancer in women. More than 75% of endometrial cancers are endometrioid carcinomas, whereas 5% to 10% are serous, 1% to 5% clear cell, and 1% to 3% mucinous carcinomas. Up to 5% are other histologies, including uterine sarcomas (i.e., carcinosarcoma, leiomyosarcoma, and endometrial stromal sarcoma). Clear cell carcinoma has been considered to have a poor prognosis because of late diagnosis with advanced disease. We report a case of 74 years old postmenopausal woman who presented in our institute with complaints of bleeding per vaginum for 5 months. Patient was diagnosed as Clear cell Carcinoma of Endometrium. Patient underwent Total abdominal hysterectomy and Bilateral Salpingo-oophorectomy (TAH-BSO). Patient was referred in our Department for Radiation therapy and was treated with adjuvant radiotherapy.