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Conventional synthesis and study of alkyl substituted 1,3- thiazole and its nanoparticles with special reference to plant pathogens of some vegetable crops

Author:

Chhaya D. Badnakhe

Subject Area:

Life Sciences

Abstract:

The synthesis, spectral analysis and biological activities of 5-phenyl-2- hydroxy-chlorosubstituted-2-amino-1,3 thiazoles have been carried out. In this case 5- (2’-hydroxy-3’,5’-dichlorophenyl)-4-(heptan-1-one)-2-phenyl amino-1,3-thiazole (K) has been screened. The compound K was synthesized from 1-(2’-hydroxy-3’,5’- dichlorophenyl)-2-bromo-1,3-nonanedione (a4) by the action of phenylthiourea. The nanoparticles of the compound K has been prepared by using ultrasonic technique. The titled compound and its nanoparticles were assayed for antipathogenic impact against some common crop pathogens viz - Aspergillus niger, Pseudomonas lachrymans, Fusarium oxysporum and Fusarium solani.

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