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Diagnostic Accuracy Of Acute Appendicitis With Significant Pre-Operative Inflammatory Markers (Tlc, Neutrophil Count) And Post-Operative Histopathological Diagnosis Encountered At Rrmch

Author: 
Dr. Shashikala, K., Dr. Usha Ramachandra and Dr. Jeena Johns
Subject Area: 
Life Sciences
Abstract: 

Background: Acute appendicitis is the most common abdominal surgical emergency and remains challenging diagnosis inspite of imaging techniques and acute inflammatory markers (TLC, Neutrophils). Aims: The aim of the study is to prove the significance of inflammatory markers (TLC and Neutrophil Count) and correlation with histopathology in diagnosing acute appendicitis. Secondly to interpret how these investigations can be used effectively to improve the diagnosis, decision making and hence reduce negative appendicectomies. Materials and methods: The study was conducted in the department of pathology and surgery. The clinical history of all the patients was taken. There was no gender discrimination and the age group included 15-50yrs. The clinical details diagnosing acute appendicitis with inflammatory markers (TLC, Neutrophil count) was correlated with histopathology sections of appendicectomies. Results: In the present study Out of 250 patients, 182 were males and 68 were females with male to female ratio were 3.1: 1.70% of acute appendicitis were in the 2nd & 3rd decade and frequent symptom was pain in the right iliac fossa, with tenderness. Total Leukocyte Count was > 11000/mm3 in 63% of patients and < 11000/mm3 in 37% patients. Neutrophil Count was > 75% in 56% and < 75% in 44% of patients. Conclusions: Simple laboratory investigations of Total Leucocyte Count and Neutrophil Count effectively improve the decision making of acute appendicitis and hence reduce negative appendicectomies.

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