Dosimetric comparison between 3-d crt and dynamic imrt in the treatment of cervical cancer

The purpose of this study was to investigate the potential advantage of Intensity Modulated Radiotherapy (IMRT) over 3-Dimensional conformal radiotherapy (3-D CRT) techniques for external-beam radiation treatment for cervical cancer. A comparison of two treatment techniques was performed using dose statistics, dose-volume histograms, homogeneity and conformity values. For IMRT plans the conformity value was closely to 1 and homogeneity value closer to 0 better than 3-D CRT. Our study indicates that the bowel volume irradiated to 45 Gy was 52.82 cc and 50 Gy was 13.45 cc for IMRT in comparison with 67.3 cc and 20.18 cc for 3-D CRT. The data shows that IMRT has the potential to greatly reduce small bowel acute toxicities when compared with 3DCRT. In conclusion IMRT has clinical advantages over 3-D CRT with improved PTV coverage and improved sparing of small bowel in the radiotherapy treatment of cervical cancer.