The study was conducted to evaluate the effect of vermicompost and inorganic fertilizers on growth and yield of tomato plants. Physico-chemical properties of the soil in both control and experimental plots were studied and interrupted with results. Plant growth (height), number leaves per plant, number of flower and fruits were also recorded. Vermicompost treated soil showed increased plant growth, number of leaves, flower and fruits compared to control soil. Significant yield was recorded on vermicompost soil. The present study suggested that vermicompost is more favorable for vigorous production of tomatoes. The vermicompost can be economically and environmentally suitable and also maintenance of soil environment.