Introduction: Pre Menstrual Syndrome (PMS) is a collection of symptoms that often appear and occur in young women, including in school-age girls who often interfere in the process of learning activities. Providing knowledge about the definition, symptoms, and cause to reduce symptoms, is expected to eliminate or reduce symptoms. Objective: The purpose of this research is to know the effectiveness of counseling with leaflet media on knowledge and its relation to behavior and its impact on reducing Prementual Syndrom (PMS) symptoms on student. Method: The research design used quossi experiment with sampling technique by Accidental sampling. The collection is done by questionnaire using a checklist format. Data processing using SSPS program Version 19. The analysis is done by univariat and bivariate with independent t test (Un-Paired) and Chi-Square test, with α (p = <0,05) at 95% Confident Interval (CI). Results: The results of this study of 98 respondents showed the most symptoms complained at the time of PMS is menstrual pain (77.8%) and feelings want to get angry (82%). The mean score of post-test knowledge in study group was 5.9 points greater than the control group (78 ± 10.58 vs 72.15 ± 16.5). The calculation of t test statistic Un-paired value of t = 3.049 with p = 0,038 indicating that there is a significant difference. The measurement of the 2nd menstrual cycle (3 months post-intervention) showed a correlation between knowledge with behavior, with a p value of 0.035 with POR (Prevalence Odds Ratio) of 2.81 (95% CI: 1.16 - 6.79.) . On the measurement of symptoms within the next 3 months, the percentage of symptom reduction was reduced to 83.3% from 59.7% with a p value of 0.02 with POR value of 3.431 (95% CI: 1.28 - 9.22). Conclusion: counseling with media leaflets (study groups) is more effective than counseling with in-focus media (control groups). The behavioral of PMS symptoms and the effect on the reduction of PMS symptoms are seen after 3 months post-intervention.