The aim of this randomized, double blind controlled trial was to verify the effectiveness of a commercially available herbal dentifrice (Dantkanti) on the reduction of plaque and gingivitis. Fifty volunteers with were randomly assigned to either a test group (herbal dentifrice) or positive control group after meeting the eligibility criteria. The present study had a controlled double blind crossover experimental design, consisted of 2 x 4 weeks experimental periods, separated by a ten day washout period. The dentifrices were distributed according to the protocol of the study to the respective group. Plaque and gingivitis assessments were carried out at baseline and after 28 days of product use. All examinations were conducted by the same calibrated investigator. Subjects were instructed to brush their teeth twice times daily using their assigned dentifrice for 28 days. There was a significant reduction in plaque levels in both the test and control groups. However, there was no significant difference between the groups. A significant reduction in gingivitis was observed in both groups, although there was no significant difference between them. The authors concluded that both dentifrices were effective in reducing plaque and gingivitis in subjects with established gingivitis.