The Purpose of this study was to evaluate the efficacy of Curcumin, a component of turmeric in the management of Oral lichen planus. A total of 30 patients were included in the study who were administered oral curcumin of dosage 300mg used thrice daily for three months in the management of clinical symptoms such as pain, burning sensation, erythema, ulceration and in reduction of inflammatory markers level interleukin-2, interleukin-6, interleukin-10, Tumor necrosis factor-alpha, high sensitivity C-reactive protein. Assessment of patients was done at 15th day, 30th day, 60th day and 90th day. Symptomatic effect of pain evaluation- there was a significant reduction in pain by using VAS score and burning sensation. Similarly, there was also significant reduction in the degree of Erythema and ulceration by using Oral mucositis assessment scale. There was a reduction in the level of inflammatory markers in the patient serum. Oral administration of curcumin showed a reduction of symptoms and inflammatory markers level in Oral lichen planus.
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