A survey was conducted in Nanded and Beed district, for the ethno medicinal plants. The paper documents were prepared from ethnomedicinal uses of wild plant species in Nanded and Beed District. The plants parts are most commonly used in treatment of various diseases are roots, leaves, whole plant bark and seeds. Inspite of vast scientific development in modern age man is looking towards traditional medicines. Due to ethno medicines many diseases are cured like jaundice, snakebite, scorpion bite, leucoderma liver and many more challenging, incurable diseases which are not cured by the modern medical science are cured by traditional medicines. This knowledge still exists in the villages. So interviews of traditional Jantas were taken, the details of plants collected, identified were noted. It is suggested that local forest management with Forest Department and NGOs needs to pay attention for Conservation of commercially important species, with sustainable harvesting methods. The cultivation and detailed assessment of the economically valuable medicinal plants is the demand of present day. Hence it is to be collected, preserved, protected and propagated for future generation.