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Extraction of some active substances from propolis and studying its inhibition activity against candida albicans isolated from patients

Author:

Alaa A. Al-Daamy, Saife D. Al-Ahmer and Noor I. Al-Baiyati

Subject Area:

Health Sciences

Abstract:

Phenolic and flavonoids compounds were extracted from propolis obtained from Al-Hussainya district in Karbala province. Results revealed that incubation period 48 and 72hourswere the optimum period for extraction total phenol and flavonoids, respectively. Where as the best ethanol concentrations for extraction of total phenol and flavonoids were 50% and 70 %, respectively. Inhibition activity of propoliswas studied against 15 isolates of Candida albicans isolated from mouth, vagina, urine and skin of the patients. Results revealed presence of significant difference in the effect of propolis extract against the C. albicans isolates of this study. C. albicans isolates 6o isolate that isolated from mouth was the most sensitive isolate among the C. albicans isolates towards the propolis extract.

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