Background: participating in any sport activity has social, health and skill related benefits due to this physical disability individuals that participated on sport activity have increase their confidence. Objective: the main objectives of this study were to find out the incidence and the factors that affect the participations of Disability students in sport activity. Methods: to find out the factors the researcher were used cross-sectional research design in Woldia University totally 46 disability students so the researcher were used all students. Result: the prevalence of the disability students were 46 from those 6 students were visual impairment the rests were physical disability. 95% of the respondents were not participating with any sport activities. All respondents were having interest to participating on sport activities. 65% of the respondents knew the benefits that participating on different sport activities. Conclusion: the respondents were described the causes that limited on physical activities. Some of the were Lack of awareness’ about the benefits of participating in sport, haven’t knowledge about the adapted sports, the attitudes of the community on their village on the disability individuals, the physical Education teachers excluded those students during practical activities at elementary and high school, there was no coordinator and motivator for participating different sports and there was no launch different sport activities for disability students in our university.