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Fine Needle Aspiration Cytology With Clinicopathological Study Of Thyroid Lesions At Srtrgmch

Author: 
Arvind N. Bagate, Rajanikant K. Musande, Sandip R. Dukare, Dnyneshwar S. Jadhav, Sheela L. Gaikwad and Grace F. Dcosta.
Subject Area: 
Health Sciences
Abstract: 

Aim: To study the clinicopathological features of Thyroid lesions at SRTRGMCH, rural set up. Method: Total 312 of THYROID lesions were studied. Patients of all age group, of both sexes with complaints of swelling over neck were included. Patients were subjected for clinical palpation, Ultrasonography(USG), Lymph Nodes examination, thyroid profile, Fine-needle aspiration cytology (FNAC) and accordingly treated with surgical and medical mode of management. All operated specimens were sent for histopathological evaluation. Results: 182 patients (58.33%) were between age group of 20 to 40 yrs with a female preponderance. Of total lesions Non-neoplastic category constituted the majority of lesions (79.80%). These cases include Nodular goiter, colloid goiter, hashimoto’s thyroiditis, lymphocytic thyroiditis and toxic goiter. Neoplastic lesions constituted 20.20% of all cases which include follicular neoplasm, hurthle cell adenoma, papillary carcinoma, anaplastic carcinoma. 56 cases underwent histopathological examination of which 43 cases (76.78%) were benign and 13 cases (23.22%) were malignant. Conclusion: Taking into consideration Histopathology report as a gold standard, correlation of FNAC finding with histopathology finding showed 78.50% sensitivity, 95.20% specificity with 84.61% positive predictive value and 93.02% negative predictive value.

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