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High sensitivity c-reactive protein in type-2 diabetes mellitus

Author: 
Teena Lal, Anand Moses, Dorairaj, V. S., Prathipa, A., Leena, P., Anandarajan, B., Muthukumar, S. and Kouser Banu, K.
Subject Area: 
Health Sciences
Abstract: 

Background: Type 2 diabetes mellitus is associated with chronic low grade inflammation. (Pickup et al., 1998) C-reactive protein is a classic marker for inflammation. (Naveed et al., 2009) Materials and Methods: Study was conducted on 96 diabetic patients attending the diabetic clinic of government medical college, Trivandrum and on 96 non-diabetic controls. Serum hs-CRP, HbA1c, FBS, lipid profile, Waist: Hip ratio, systolic and diastolic BP was measured in cases and controls and the results compared. Results: Mean serum hs-CRP was significantly higher in cases than in controls (p=0.009). Conclusion: The new pathogenetic vision of diabetes mellitus includes inflammatory pathways playing pivotal roles its development and progression.

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