Background: The process of gastrostomy has been used for long time for health purposes while the procedures been evolving according to the requirements and advancements of times. This research study is based on the comparison between Percutaneous Endoscopic Gastrostomy and One-Step Gastrostomy regarding the infectious rate in hospitalized Children at a Tertiary Care Hospital in Jeddah, Saudi Arabia. Methodology: Our retrospective study of 132 Patients, at king Abdul-Aziz university hospital KAUH from 1st January 2002 to 31st December 2019 was approved by the Institutional ethical committee, File numbers were reviewed from Log Sheets in the endoscopy unit & hospital record archives. The inclusion criteria for the study were below 14 years of age, regardless of their diagnosis who had gastrostomy tube placement. And the exclusion criteria Patients who had done surgical gastrostomy. Results: According to the research study, the rate of infection was considerably low for the participants with the one-step Gastrostomy. The difference was around 10.62%. Conclusion: The research concludes that the One step Technique is better than the pull-through technique regarding infection rate, but further large study needed for solid conclusion.
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