The use of platelet concentrate in dentistry is contemporary and revolutionary for the tissue regeneration. Platelet concentrate carries cells, growth factors and some cytokines which is becoming a valuable adjunct to promote natural healing in many procedures in periodontal surgery. This is the goal in periodontal regenerative surgery that is to achieve complete wound healing and regeneration of the periodontal unit. Platelet concentrate in the form of Platelet Rich Plasma (PRP) was first to be introduced and being extensively used for regeneration. Recent development of Platelet Rich Fibrin (PRF) by Choukroun revolutionaries its use in surgical procedure because of ease of preparation and increase amount of platelet with active growth factors available is more than PRP. It remains controversial because of its duration of growth factor release. Within last 2-3 years there are research being attempted to increase the amount of platelets in fibrin mesh by Shahram Ghannati et al. and increasing the fibrin polymerization to incorporate platelet for more duration by Mustafa Tunali et al. This article is being attempted to review past and present development of platelet concentrate and its effect in odontogenic cyst with bone graft.
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