The human GIT has normal flora of bacteria which play important role in homeostasis of human gut. The imbalance of gut flora is induced by traditional treatment such as antibiotics which causes increased prevalence of disorders and diseases. This disruption of host microbial can be manipulated by using probiotics and prebiotics. Probiotic is microorganisms that produce metabolic by-product which exerts beneficial effects on biological functions and modulate the immunity of the host. While, prebiotic is a fermented component or non-digested food which though to stimulate or activate the microorganisms in the human gut. In conclusion, probiotics and prebiotics can be used to treat gut disorders due to imbalance of normal flora which is reported to cause many gastric diseases.
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