The main purpose of the research was to establish the relationship between psychosocial factors and virtual teaching in conditions of social isolation, in university students in Lima. The research method was non-experimental, with a descriptive correlational design. For the statistical treatment of the data, the Pearson r correlation coefficient was applied. The study sample consisted of 80 university students of both sexes, between 18 and 25 years old. Two scales, elaborated by the authors, were applied to them, the same ones that were subjected to validation and reliability processes. The results indicated that there is a strong positive correlation between psychosocial aspects and virtual teaching, corroborated by an r = 0.777 obtained. It was concluded that in adequate psychosocial conditions, students adapt better to the virtual teaching modality in pandemic conditions by Covid 19.