Avicennia marina were extracted from different solvents like Acetone, methanol, diethylether, ethanol, ethyl acetate, petroleum ether, chloroform and aqueous extracts against 12 bacterial strains. The present study exhibit maximum antibacterial activity was recorded from chloroform extracts against Enterococci sp. and minimum activity was noted from ethyl acetate extract against Klebsiella pneumoniae, Enterococci sp., Salmonella sp. and Shewanella sp.