Study to evaluate oral microbial flora in CVD (cardio vascular disease) patients from Guntur District of Andhra Pradesh

Over the decades our understanding of the pathogenesis of Cardiovascular Disease(CVD) has increased, and infections, including those caused by oral bacteria, are more likely involved in CVD progression than previously thought. The two disorders share several common risk factors, including cigarette smoking, age, and diabetes mellitus. The focus of this study is to assess whether available data support a causative relationship in systemic inflammation and endothelial dysfunction. Oral samples were collected from 19 patients with cardiovascular disease. The microbial flora was evaluated by drawing swab samples from the oral cavity by using sterile swabs and on Grams staining, both Gram Negative and positive organisms were found. Most of the patients had mostly gram positive organisms, only few patients showed both gram negative and positive organisms. Two cultures 3 and 5 showed coagulase and catalase positive. Biochemical tests of both 3 and 5 culture were performed and Culture 3 biochemical characteristics were little different from the normal Staphylococcal biochemical tests. Whereas Culture 5 showed similarities with the normal Staphylococcal biochemical tests. Culture 5 was taken and antibiotic sensitivity test was performed. Culture 5 was sensitive to Gentamicin followed by Linezolid, Penicillin G and Furoxone. This matches with the literature data wherein most of the CVD patients show Staph.non aureus organisms, which are responsible for them developing the CVD conditions.