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Sublingual Versus Vaginal Misoprostol for Cervical Ripening Before Hysteroscopy

Author: 
Samy A. El-Azeem Saad, Mohamed A. El-Hadi Farag, Mostafa A. Allah El-Sayed and Aml El-Sayed Ali El-Fawal
Subject Area: 
Health Sciences
Abstract: 

Study design: Comparative clinical trail. Objective: To evaluate the efficacy of misoprostol (sublingual versus vaginal) for cervical ripening before hysteroscopy. Patient and Methods: Sixty women who were admitted to Banha University hospital department of obstetrics and gynecology for surgical hysteroscopy. The sixty women were divided into two groups. Group one 30 cases received 400 μg misoprostol (two tablets each tablet 200 μg) under the tongue 6h before hysteroscopy. Group two 30 cases took 400 μg misoprostol (two tablets each tablet 200 μg) administered into the posterior fornix of vagina by investigator 6h before hysteroscopy. The degree of cervical dilatation. The duration of diltation, hysteroscopic and drug complications were recorded for all cases. Results: There were statistically Significant difference between sublingual group and vaginal group as regard cervical dilatation and operative time. cervical width in the sublingual group (6.4+0.9). in vaginal group (5.4+1.3) Operative time in minutes (1.095+0.22) in sublingual group, (2.05+0.150) in vaginal group. No significant difference between sublingual and vaginal group as regard post hysteroscopic complication. Conclusion: Sublingual administration of misoprostol is more effective than the vaginal route for preoperative cervical ripening.

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